CCRAS has developed a polyherbal formulation, Ayush-82 for the management of Diabetes mellitus. Diabetes mellitus (Madhumeha) is a group of metabolic diseases marked by high level of blood glucose resulting from defects in insulin production, insulin action or both. Diabetes may lead to serious complications involving multiple organs. Ayurvedic literatures vividly describe about the aetiology, pathogenesis, prognosis, complications, its management and scientifically attributed the causal relationship of dietary, lifestyle, environmental and genetic factors.
CCRAS has developed a polyherbal formulation, Ayush-82 for the management of Diabetes mellitus.
Acute Toxicity Studies of Ayush-82 administered orally in Swiss Albino (I.B) mice revealed no pre-terminal deaths, no toxic signs and abnormal behavior in the animals at 10 times of intended therapeutic dose.
Sub-Acute Toxicity Studies of Ayush -82 in Wistar rats showed no significant effect in the blood biochemistry, haematology and weight of the vital organs in comparison to the control suggestive of its safety.
The study has been carried out on 886 patients (497 completed cases and 389 drop outs) at Council’s peripheral Central Research Institutes wherein Ayush-82 was administered thrice daily. The results indicate statistically significant reduction in fasting and post prandial blood sugar level along with clinical improvement. No adverse events were reported during the treatment period1, 2, 3, and 4.
15 g per day in 3 divided doses along with 500 mg Shuddha Shilajita twice daily3,4.
- CCRAS Research an Overview, Central Council for Research in Ayurveda & Siddha (CCRAS), Year:2002, Page no. 21.
- Annual Report of Central Council for Research in Ayurveda & Siddha (CCRAS), 1982-2007.
- Hypoglycemic effect of a coded formulation : Ayush-82, D.P.Chowdhary et al, JRAS, Vol. XIX, no. 3-4,(1998) pp.107-115.
- An effective Ayurvedic hypoglycaemic formulation, V.N.Pandey et al, JRAS, Vol. XVI, no. 1-2,(1995) pp.1-14.